DPCstruct | MC13899

Metacluster Properties and Pfam Annotations

Number of structural domains39
Mean domain length (aa)223 ± 33 aa
Standard deviation of domain lengths32.96
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score85.94
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)18.15
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A849L0X2 21-278 ANAPHQHAFVLLGSETIFAVHMTQYHHEEHKYQLVMKLALPAEAKSRLDDLRARFPADTFILSNGDAESDLFTIPDLPAGRRRSFNA…
F8P8Y2 611-845 VVQGEDRLYLVYKACFNTASSRYQHVITGDIPITSKQEYLDNKRRIPFATFTARTLENIEITSFINKNSFSIEITSTSPTGTIAILE…
A0A2I2GMI9 704-959 None
A0A2G0Z365 11-222 None
A0A7W3R7G4 29-247 None
I0WLZ1 105-357 None
A0A420TXP0 1-223 None
A0A5N6XMW1 243-480 None
A0A1J9RPZ9 749-952 None
A0A270QYN7 11-267 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.