DPCstruct | MC13875

Metacluster Properties and Pfam Annotations

Number of structural domains212
Mean domain length (aa)144 ± 29 aa
Standard deviation of domain lengths28.61
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score87.11
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)31.40
Pfam Score96.22
Assigned Pfam label(s) PF16639- PF00223- PF05695- CL0304- PF00329

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E6SI90 198-342 None
A0A6A5L104 632-772 None
A0A6A5L5L9 1105-1241 None
A0A6A5L9R2 172-322 None
X8B2J0 17-161 None
A0A7C5BE79 2-100 None
A0A7C7Y4L7 91-234 None
A0A2A3EMC6 246-396 None
A0A520F1D1 257-481 None
A0A7C2S7G8 1-122 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.