DPCstruct | MC13875

Metacluster Properties and Pfam Annotations

Number of structural domains212
Mean domain length (aa)144 ± 29 aa
Standard deviation of domain lengths28.61
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score87.11
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)31.40
Pfam Score96.22
Assigned Pfam label(s) PF16639- PF00223- PF05695- CL0304- PF00329

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0G1FDI5 1-107 MREMDVAFVEGAIASEAQVAKLQQIRTLAKKLVAIGACAVVGMPSAQRNNFDEATKAEIAPFLLQFHHADKIRTIADIVTVDDRVPG…
X1RAC4 3-129 LKFLIASLTSCTGCISALISLDIFPQFLERTKIEYFPFISDNLKINECDIALVEGCVSEKNQIEYLQEIRKNAKKLYALGTCSAFGG…
A0A7K0PZN7 1-104 None
G4TH23 6-138 None
L0HK62 66-186 None
A0A101G1K4 39-217 None
A0A4T0J692 96-252 None
A0A7V4JRC2 76-255 None
L0AJC7 27-209 None
A0A521S0D4 15-184 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.