DPCstruct | MC138

Metacluster Properties and Pfam Annotations

Number of structural domains2873
Mean domain length (aa)224 ± 38 aa
Standard deviation of domain lengths37.85
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score87.14
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.37
Mean intra-cluster sequence similarity (%)11.79
Pfam Score75.78
Assigned Pfam label(s) PF01016- PF20888- CL0329- PF20254- CL0286

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Y8V5J7 10-168 VITKEQDFSSYRLLIVPMLYLASEETIARLKAFSANGGTLVMTYISGIVNEYDLTYLGGWPQDLQELFGIVPVETDTLYPGDKNAVR…
A0A842VUT9 4-220 KALCVYGGWKGHTPKKSMKKMIKILQDEGFEIVKKKTLDAYKDRKLMESLDLVVQCWTGGNLEKDQEDGLSYAVMDGVGLVGWHGGL…
A0A3A0B6E9 589-822 None
A0A257QEB0 44-292 None
A0A0N0TPJ9 17-231 None
A0A5S6QF88 28-234 None
A0A5S6QT58 333-579 None
A0A0G1HQQ6 67-250 None
H0EHH0 1-203 None
U1P7M5 8-201 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.