DPCstruct | MC13789

Metacluster Properties and Pfam Annotations

Number of structural domains65
Mean domain length (aa)107 ± 18 aa
Standard deviation of domain lengths18.41
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score77.63
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)43.68
Pfam Score98.75
Assigned Pfam label(s) CL0123- PF01776

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S3XE72 2-79 LQERIKVGGKAGALGDTVTVTRDKTKITVTSDSTFSKRYLKYLTKKYLKKNNVRDWLRVISSNKDRNVYELRYFNIAE
A0A2K6V0B9 1-95 VAPRKDKEPKKSNWKFNLDLSHPFLQEKVKVNGKTGNLRNVVHNEPFENNITVVSEKQFSKRYLKYLTKKYLKKNSLCDWLRVVELC…
A0A287X281 14-104 None
A0A816Q1S7 838-960 None
A0A4Y1QZW5 139-254 None
K4AEP2 95-229 None
A0A7R9T4C0 165-274 None
A0A842XV93 2-92 None
A0A077ZYM8 817-932 None
A0A811ZN08 4-87 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.