DPCstruct | MC1378

Metacluster Properties and Pfam Annotations

Number of structural domains174
Mean domain length (aa)101 ± 21 aa
Standard deviation of domain lengths21.25
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score79.42
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)20.17
Pfam Score94.64
Assigned Pfam label(s) CL0123- PF08706- PF18326

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0M9DHD5 2-74 WFVEEHCELIPEQFEYSRQLYQYYKQMCLENGLQPISQTKFNKSLQNDYPKQLLRTEESNSKRIIFKGIKIRR
A8SI46 9-88 EDMDILGPYINENCIINPMAKVESRKLYDDYKKWCYQNDELELKNRSFYRQLVTRGFKKKRGTANKIFFYGIGLKKEQSY
A0A2A4JU32 1-112 None
W9AIZ4 65-159 None
Q6FS37 368-457 None
Q6FXL2 152-279 None
A0A1V5FMB1 661-744 None
A0A1D2N8M7 608-740 None
A0A021X456 166-250 None
A0A1P8WR89 1169-1249 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.