DPCstruct | MC13778

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)151 ± 12 aa
Standard deviation of domain lengths11.77
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score81.98
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)18.19
Pfam Score0.00
Assigned Pfam label(s) PF10067- PF20327- PF07301

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5C5VV54 131-265 FAMMARTYSKPWKLMTVTCLLPAFAASSSYAIQLWLFSERMPQLQWIGIAATVGLIVGLIRARTHEIYYENGQIMARRTAAYLIIWA…
A0A5P9Q686 32-186 DAAATANHAALVVVLVVVAWLIVRQLTARRLDPRSTLAWVLLAVGAAETLAYLTGAHVTARDVALLVVSAAVGGALAVVRARTMRLW…
K0F8X8 4-156 None
Q97G64 2-151 None
A0A7I8EYW7 2-129 None
A0A846J7X2 10-159 None
A0A7G9SE11 7-171 None
A0A7R7CRA8 166-321 None
A0A355EM59 5-169 None
A0A1C5ALR7 3-149 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.