DPCstruct | MC13724

Metacluster Properties and Pfam Annotations

Number of structural domains687
Mean domain length (aa)194 ± 39 aa
Standard deviation of domain lengths38.71
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score87.06
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.40
Mean intra-cluster sequence similarity (%)13.13
Pfam Score100.00
Assigned Pfam label(s) PF03167

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y2EW92 20-220 AAPSVYASLPQKVPDCIREGLTLLIVGLNPGVLTAKTGLHFASPTNLFWPLLYESNIITRPMKAQEGCACLVNEFDIGITNIIDRPT…
A0A4R0INC4 220-393 PVTVARHFAKVPSYADFRELFWHDWGPVFYRGRLNRKARLLAIASDPGPTERVAGRTLVGDAGQRVQGFLAKLGLTRSYALVNAYAY…
A0A1Y6BZT2 187-368 None
A0A7C1C7K0 14-186 None
A0A1H3XZ11 1-229 None
A0A1H3XZ66 103-357 None
A0A1H6L279 17-243 None
A0A1E8Q171 317-530 None
A0A2H0DTT0 2-129 None
A0A844TBZ5 274-453 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.