DPCstruct | MC13675

Metacluster Properties and Pfam Annotations

Number of structural domains37
Mean domain length (aa)212 ± 35 aa
Standard deviation of domain lengths34.52
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score86.72
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)20.53
Pfam Score100.00
Assigned Pfam label(s) CL0316

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V2F107 3-195 GISATTLKIIGMIAMTIDHIGYFLFPQIEAFRIIGRIAYPIFAYMIAEGCRYTRNKVKYLLSVLGVGCGCSAVSYITEGSLYQSILI…
A0A1A9M9J5 6-215 REFLKWLAAAFMTGDHVLKILAIGYVPVVTELGRVAFPLFALVLAYNLAQPKADVEKSVKRLFLWGLIATPVAAIAFQRVFPLNVLL…
A0A2A4QU23 23-258 None
D0BL26 7-247 None
A0A1V5GP52 10-259 None
A0A4Q5EYG4 1-228 None
A0A650MUU4 1-186 None
T2RFZ4 1-149 None
A0A847CBA8 11-238 None
A0A5C9B160 225-438 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.