DPCstruct | MC13673

Metacluster Properties and Pfam Annotations

Number of structural domains300
Mean domain length (aa)130 ± 20 aa
Standard deviation of domain lengths20.45
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score82.64
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)14.97
Pfam Score87.56
Assigned Pfam label(s) PF11042- PF07179- PF11360

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1W1YE04 74-203 GQYTGSVGDLINNYRNGEIEESKFYESLGDVVLYYADPTGVDREGNTADYTLPAAEGCRYLPVFDSYAHTRNYYVEEGRVRITIKRE…
A0A413WQT6 55-164 VTQAESDVLETFCERVEENGLVFGLSAEQDEGWAYAPSHVEDTDVLLFFSSRELALACRVKEWADYHVIELPVELFLERWLPNMSDD…
A0A101S9T1 79-192 None
A0A2A2SDV1 136-261 None
A0A4Q9KD30 128-267 None
A0A2A3ITV8 192-337 None
A0A6J4H583 41-140 None
A0A838JVG4 25-164 None
A0A0N0MNG1 3-123 None
A0A1G6GMH2 407-547 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.