DPCstruct | MC1363

Metacluster Properties and Pfam Annotations

Number of structural domains510
Mean domain length (aa)126 ± 25 aa
Standard deviation of domain lengths24.91
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score86.54
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)21.66
Pfam Score98.40
Assigned Pfam label(s) CL0111- PF00305- CL0063- CL0184- CL0487

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R0MDM2 26-138 None
A0A0F9ESB2 42-161 None
A0A2E4G0I3 179-289 None
A0A4P5SN13 142-279 None
A0A367ZVI4 185-297 None
A0A7S4IEH5 18-140 None
A0A7Y5VPQ7 108-217 None
A0A7Y5UST8 131-254 None
A0A7Y5RSG0 296-434 None
A0A7Y5JLC4 382-496 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.