DPCstruct | MC13611

Metacluster Properties and Pfam Annotations

Number of structural domains33
Mean domain length (aa)257 ± 50 aa
Standard deviation of domain lengths50.11
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score80.98
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)17.37
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W4SBC8 3-291 QESIIRYWHAVELLQPQSAPKLKKRSNRYEAFIHDTPIQRPLLPWTPESIVSKQKLPKKRIWSHTLYAHLYDSRLVAEKLDAMYGAD…
K8XEX2 8-282 KADVVAFWRAIELFSPQTVPKIDRFDTHAPVERVTDGKPLPWEAGHRLHGRSTRRGYQRQHIVYLGVYRIDDVWMAVDDILDPGTEN…
A0A529M875 122-412 None
A0A512C1T4 142-407 None
A0A2E0R129 131-289 None
I0GU00 5-309 None
U2CXI4 4-286 None
A0A368NKC9 120-410 None
A0A227KGB6 11-289 None
N2AKD5 1-289 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.