DPCstruct | MC13604

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)151 ± 11 aa
Standard deviation of domain lengths10.69
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score85.97
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)43.31
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
G2D905 1-126 MLAGLPPLWWLVPPDKEQDYQRYTENLLAKRFVEPSDLLDLGGLDQVPAGEFFGAALWQLYKGIDSPYKSILKIFLMEAYSKHYPDT…
S4WAZ0 1-163 MKSDNNIFGESDSESTGSALAKLLKEEMYRTMIIVTGKIPFWLIAPVDCDDNRYTELMGMIQNNETLLKREEYIDMGNVDDISDGEF…
A0A380QEA4 2-150 None
A0A378N8I6 1-160 None
A0A2A5CWB4 181-333 None
A0A0B8PYN4 38-195 None
A0A6N0HSX5 177-325 None
A0A379X3H2 33-185 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.