DPCstruct | MC13548

Metacluster Properties and Pfam Annotations

Number of structural domains306
Mean domain length (aa)105 ± 21 aa
Standard deviation of domain lengths21.20
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score77.90
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)17.56
Pfam Score56.42
Assigned Pfam label(s) CL0220- PF04155- PF01221

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183N7Q3 1-76 MPVDMQQDAVDLCYQGIENFKEEYEIAKYLKKEYECKYGSIWHCIVGKSFGSYISHEEDGFIFFHLHGYYVMLFKA
A0A553NXJ2 20-119 YAQFLNRTRVAPIVKYCTLGTDASDEALDIILAACELLPWDNLGISNHIKNHLDDRLGTPWHVVVGESFAFEITSEGGDLMFVYYGS…
A0A0R3UGQ0 25-118 None
A0A0D8X7S5 706-826 None
A0A0R3U645 645-770 None
A0A0D9V1Z1 340-444 None
A0A0N5CVE4 81-202 None
A0A0D8XM86 2-66 None
A0A504X728 2-103 None
A0A2K5NXH6 3-74 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.