DPCstruct | MC13540

Metacluster Properties and Pfam Annotations

Number of structural domains191
Mean domain length (aa)212 ± 33 aa
Standard deviation of domain lengths33.24
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score84.86
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)24.92
Pfam Score68.35
Assigned Pfam label(s) PF04998- PF04992- PF04983- PF00623- PF05000

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q8EWX0 692-905 None
A0A7C7K7W5 249-462 None
A0A2K3NSM6 176-396 None
A0A0L0FF33 6-190 None
P27625 783-1018 None
A0A061GWN1 2-157 None
A0A438CN79 347-574 None
A0A5C7HE17 328-534 None
A0A385GNK3 1-172 None
A0A0C3KJJ1 259-521 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.