DPCstruct | MC13536

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)110 ± 7 aa
Standard deviation of domain lengths7.03
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score73.01
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)42.53
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
C5Z0Z4 57-167 SSSSEGGRLVDEDMATLRRRIREARAEDDGIFDADVDAGIPLPTEWTELERRHHGSYVAGVRSAVALLEVLLVNTRPGLGAGLLAVL…
A0A835VAE9 2-100 GQKVDEDMIVLRLRIHEMRAIERNEEPPSHWMEWEKRCFSSYAADVCMAVGFLQTLLMSTRPSFAVALVLTFALSVTSSGFLLLCHL…
A0A4U6VDG4 168-287 None
A0A5C7ILI3 25-139 None
A0A1E5UK00 60-178 None
A0A843WX99 58-155 None
A0A1J7HKL5 1-109 None
A0A2N9FNU9 53-156 None
A0A444CRJ2 170-276 None
A0A833R3N2 1-114 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.