DPCstruct | MC13488

Metacluster Properties and Pfam Annotations

Number of structural domains739
Mean domain length (aa)91 ± 14 aa
Standard deviation of domain lengths13.53
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score80.52
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)27.51
Pfam Score99.43
Assigned Pfam label(s) CL0023- CL0713- CL0105- PF00173

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0DIU9 187-276 None
A5DKW9 76-173 None
A0A1R2BX69 5-117 None
A0A074Z083 258-356 None
A0A6A2X8G2 29-131 None
M1A8Z8 125-279 None
A0A812LNG7 522-619 None
A0A1B5L5X4 407-495 None
A0A812KPX8 354-463 None
A0A2Z3KTC5 778-871 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.