DPCstruct | MC13488

Metacluster Properties and Pfam Annotations

Number of structural domains739
Mean domain length (aa)91 ± 14 aa
Standard deviation of domain lengths13.53
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score80.52
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)27.51
Pfam Score99.43
Assigned Pfam label(s) CL0023- CL0713- CL0105- PF00173

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7S2TJL1 13-101 EQHDTADRMPEQKQYTIAEVAKHNKNDDCWIIINGGVYDVTKFAKYHPGGKKILLKEGGKDSSKKFKMFHGGHVLKKYDKKLKIGTV…
A0A0K0FG29 2-80 TTFTASEISKNNTPRCLWIIYKGNVCDITDFYPNHPGGSALLKYAGKDITKIMSNVPLHNIAMSKINKVLEERIIGQLK
A0A7L4PFQ1 106-179 None
A0A7R9T3K4 21-111 None
H0EHI8 2-89 None
A0A7R9PNY1 2-98 None
A0A7R9PW79 24-123 None
A0A1V2LN82 492-561 None
A0A654HCN2 3-90 None
F4QAG4 127-213 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.