DPCstruct | MC13456

Metacluster Properties and Pfam Annotations

Number of structural domains50
Mean domain length (aa)68 ± 9 aa
Standard deviation of domain lengths8.85
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score73.19
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)47.41
Pfam Score98.65
Assigned Pfam label(s) CL0199- PF00187

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2P5W8F0 5-76 KLYILLTSSSVAILLLCLGASAEQCGRQVGGALCPNRPCCSQHGWCGTPSKYCGTGCQSQCSGSTPTPILPS
A0A835BRE7 1-46 MMTHAQQCGSQAGGAVCANNLCCSQYGYCGLGGDYCGSGCQSGPCY
A0A446XUK3 1-70 None
A0A835ER57 1-60 None
A0A835AQZ6 52-116 None
A0A2T7EE32 7-83 None
A0A1U8KG53 8-77 None
A0A6J0NWX0 2-70 None
P85966 11-108 None
A0A7I4EJY8 209-270 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.