DPCstruct | MC13428

Metacluster Properties and Pfam Annotations

Number of structural domains145
Mean domain length (aa)87 ± 23 aa
Standard deviation of domain lengths23.27
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score83.53
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)38.79
Pfam Score97.53
Assigned Pfam label(s) PF00285- PF00237- PF07123- CL0123- PF00203

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2I0RXC5 468-583 None
A0A6A5L6A7 471-544 None
A0A4U6UZ70 1-51 None
Q2EEV9 19-108 None
A0A834L4U7 265-380 None
A0A834L4E5 63-181 None
A0A812TC89 600-685 None
A0A0V1BVR6 93-207 None
A0A817AGD8 585-698 None
A0A4Y7IKK4 54-131 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.