DPCstruct | MC13428

Metacluster Properties and Pfam Annotations

Number of structural domains145
Mean domain length (aa)87 ± 23 aa
Standard deviation of domain lengths23.27
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score83.53
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)38.79
Pfam Score97.53
Assigned Pfam label(s) PF00285- PF00237- PF07123- CL0123- PF00203

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2S4WGF9 10-174 None
A0A367LPQ4 389-465 None
A0A816J3F7 141-215 None
A0A2S6VSG8 4-65 None
B0I1Y4 27-105 None
A0A0G4MMI7 331-441 None
H0V238 29-128 None
A0A4U0VZ60 487-557 None
A0A4S4D722 34-150 None
A0A445CKC1 42-159 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.