DPCstruct | MC13379

Metacluster Properties and Pfam Annotations

Number of structural domains753
Mean domain length (aa)262 ± 51 aa
Standard deviation of domain lengths50.76
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score83.66
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)12.19
Pfam Score92.62
Assigned Pfam label(s) CL0323- CL0125- PF17951- CL0257- CL0042

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7K1J1X0 3-176 AMYDKGKAAVVVTEAETKLKTGELLWTTRSSVFIRGEGGWDGERGPSGPQNEPPAKAPDHEVTLQTSPDQAFVYRLSGDRNPLHTDP…
A0A7X1H0G6 37-292 AAAGRASTTVRADSLHVNADGTLDPTAHLELMGQTFAAAKSWRDRQQGRPPRVGFLAGATGMDCLDTARIGDQLTIVIKQTGAFGAF…
A0A2R8ATV1 26-325 None
A0A0F7SCW6 441-789 None
N4WEB0 16-159 None
A0A3D3Q8A9 30-276 None
A0A538QN24 105-276 None
A0A538QT77 352-612 None
A0A3S0Z7I3 104-361 None
A0A099P5Y9 377-634 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.