DPCstruct | MC1337

Metacluster Properties and Pfam Annotations

Number of structural domains55
Mean domain length (aa)64 ± 5 aa
Standard deviation of domain lengths5.49
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score78.94
Mean fraction of residues predicted as intrinsically disordered0.43
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)56.82
Pfam Score100.00
Assigned Pfam label(s) CL0021

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A9P8H3 1-62 MDSQIKHAVVMKIMGRTGSRGQVTQVRVKFLDDPNRFIMRNVKGPVREGDVLTLLESEREAR
A0A1B0GL06 2-62 EKPVVLARVIKVLGRTGSQGQCTQVKVEFIGEVNRQIIRNVKGPVREGYVRTIICDFCPES
A0A6P5N4L0 19-83 None
A0A7J4JDJ1 18-93 None
A0A497I363 27-91 None
A0A0H5BKM3 14-86 None
A0A7R9KME6 504-564 None
B5DH72 1-58 None
A0A4U0W6G4 86-149 None
A0A507FDV4 564-629 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.