DPCstruct | MC13350

Metacluster Properties and Pfam Annotations

Number of structural domains30
Mean domain length (aa)300 ± 48 aa
Standard deviation of domain lengths47.54
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score71.78
Mean fraction of residues predicted as intrinsically disordered0.88
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)23.79
Pfam Score89.50
Assigned Pfam label(s) PF04935- PF15459

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6J1TE70 9-297 KVNLDRLREKLNSEYNFITSVLDRVPSIYWQGNSNDGTDEAENAEGSKWKPDAGSKVVANANKKPRATTIEELQERLEACKAKKAQG…
A0A7F8Q8G6 2-213 FAPFLQGHNTELSPATLEKRRRRKQERDRKKRKRRELRAKEKVAKATEAAKPPHELSHEQPHEEVQPGLLFNKVEVTEEQAASKAQR…
A0A2N1JEF0 51-387 None
A0A3P7IWA7 107-358 None
H0ELA9 4-299 None
B6AB18 45-279 None
T1PJW2 1-213 None
T1F8A0 2-305 None
A0A4Y9XVV6 550-896 None
A0A5C6NJY0 1-269 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.