DPCstruct | MC13343

Metacluster Properties and Pfam Annotations

Number of structural domains60
Mean domain length (aa)229 ± 70 aa
Standard deviation of domain lengths70.10
Length coefficient of variation0.31
Mean AlphaFold2 pLDDT confidence score72.74
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)16.68
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
B6IE43 962-1091 NKKKHFTCSLCHKKIEGQIGRVESREDKLILMIAAILDHRFEMDIAASFVRSRREFIVCSQHFQSAIDRIFLFLSIKHMNQLSMCRQ…
A0A7I4YXB9 3-234 HMVFCDICNRKRPVKGARNASCQPKRNAVLLACLVKLNIISLNRARRIFDELVQTTTPTRNHKRFCREHYAESVSFLAAMVEMRTGR…
A0A368G4A1 2-165 None
A0A368G491 1-227 None
A0A0B1S9N0 229-408 None
A0A368G168 232-665 None
A0A368G0Z5 244-506 None
A0A2H2IEU7 306-480 None
A0A2H2HYQ1 641-763 None
A0A0M3I943 107-322 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.