DPCstruct | MC13298

Metacluster Properties and Pfam Annotations

Number of structural domains120
Mean domain length (aa)185 ± 35 aa
Standard deviation of domain lengths35.19
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score80.88
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)18.99
Pfam Score80.59
Assigned Pfam label(s) PF15228- PF16922- PF05916

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A452Z8N4 9-114 RECGEHNAQFQALIRKMVEQNLDIETTRNEDHYGAAIHHLSLLRNKRCLMAYMYNRAETIRSFRWKIGPVLPHEIQEKLNFSEKEYF…
A0A3M7R5T1 34-238 QTGAKWIKNKKIRMFCQKSFELIKQLDSNFNSTHELSPFNEDNVRYTFEECKTLFAQNQIDVQPVLQGDNSNLPTIQMRHAALQRNK…
A0A835GY70 6-178 None
A0A0K0EE25 604-817 None
A0A099P5E3 23-199 None
A0A654HC74 213-440 None
A0A811MVS1 190-379 None
C4JTP0 1-185 None
A0A1Y2HTJ1 6-190 None
A0A7R8X8Y7 797-1005 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.