DPCstruct | MC13294

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)85 ± 10 aa
Standard deviation of domain lengths10.03
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score87.65
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)23.83
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
M5SXT2 5-73 VESKLCELGSLEPREFPLTQREVVRRGKTCAIYFCLHGPRSVKLTAIADFKTRSMVFYGSDGVRRETVR
A0A5B9R217 8-89 RIDFTQLRKMVASMLAELGQLEFDAFPMTERVVVKKGEACGVYFCLHGPRNVKITAICDLKKRTIIYYGSDGVRAQQASIPA
A0A7C5FZM9 8-90 None
A0A5C6AJB5 12-100 None
A0A517T4N3 27-101 None
A0A2D7HM32 1-98 None
A0A3E0P6S5 47-128 None
A0A7V4PBT2 1-85 None
A0A3L7VG45 7-85 None
A0A3L7P441 26-115 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.