DPCstruct | MC13253

Metacluster Properties and Pfam Annotations

Number of structural domains209
Mean domain length (aa)209 ± 30 aa
Standard deviation of domain lengths29.78
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score85.58
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)18.37
Pfam Score98.72
Assigned Pfam label(s) CL0328- CL0318

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7X5WHP8 15-243 SERLPRGVIRYQWVYLWHWPIRAMHWIAALCIVVLVVTGFYIGAPYFLTAGEPSGHYLMGWARFLHFAAAGVLVATGIVRVYWLFKG…
A0A5Q2MXW8 4-210 SKGPMVEKFPLDQRVVHWIGSISFIICALTGLLLFTTALDFLAPLFGGKATAGRIHLISGIVFAITPLIALIWNGKNLIHFLRDISH…
A0A0F8MGC9 2-224 None
A0A1F9K192 2-210 None
A0A351G850 71-300 None
A0A1V5RWY4 11-231 None
A0A3M1EGQ9 4-224 None
A0A2U1S1B1 51-240 None
C5AHU2 13-214 None
A0A3A4Z1T4 3-232 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.