DPCstruct | MC13227

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)122 ± 19 aa
Standard deviation of domain lengths18.94
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score77.57
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)44.48
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A015I629 1-117 MPDKVYEWRKFLQNLVENFEMFFADELSGAVDALSSEEFGVFFDNLEKGINKALEHFEKWFLSWLHLPLVICHLGGDNGKSFASSFH…
A0A397VT39 1-152 MPDFIVRKTMKLRNIVEDPYLFFEKELLENINLLEDHQLNELILDLERGTKKALELHQKWLDCWLHLLLSICHLGVKYGHEFARSFA…
A0A372QES5 1-103 None
A0A372Q6G4 1-117 None
A0A397VCQ0 81-195 None
A0A2N1MTP9 9-170 None
A0A2Z6R9H1 121-248 None
A0A397W4Y3 6-130 None
A0A397VZ19 1-106 None
A0A397VTI3 275-405 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.