DPCstruct | MC13220

Metacluster Properties and Pfam Annotations

Number of structural domains38
Mean domain length (aa)135 ± 18 aa
Standard deviation of domain lengths18.21
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score90.42
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)28.69
Pfam Score100.00
Assigned Pfam label(s) CL0023

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A136H8A2 9-132 IANRYAEGVVSGLINECKYVVLACQRHLSDINKSNSKEFNYWFDENSAAAACESIQQYKHKKGLWARKNLTLKLQPWQLFQLVSVFG…
A0A6M1CMA6 1-116 TRAERNILWCERNIYIPEGKFVGQPLKMAEFMKDDFRAIFDNKHGTRRAIISRGRKNAKTVETAMLMLLYLVGPEAAPNSQLYSAAR…
A0A377ZHC1 5-122 None
A0A380DKS4 2-118 None
A0A198FB69 6-162 None
R9IVY1 17-140 None
A0A0F9EY70 6-149 None
A0A2G4IMA1 14-151 None
A0A839PBE5 2-141 None
A0A1X7SMQ9 8-142 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.