DPCstruct | MC13199

Metacluster Properties and Pfam Annotations

Number of structural domains264
Mean domain length (aa)147 ± 24 aa
Standard deviation of domain lengths23.53
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score89.42
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)25.51
Pfam Score99.03
Assigned Pfam label(s) CL0139- CL0055- CL0028- CL0059

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Y0ISF9 20-160 YTQGGLAWNGKWGSLRTTANTAFLAGVYHDTVDNDSRYHSFTQKQIDYILGDNPRNSSYVVGFGNNSPENPHHRAASGLEKINASED…
A0A6A0GZ91 14-149 WGSLSSATQIAFIALKAGKAADLGIEPEVNRAWAEQQINYALGSSGRSYLIGYGDNYPLRPHHRGSSCLDLPEVCDDGWALNQPGPN…
E4XPX2 1123-1261 None
A0A383W5M1 12-291 None
A0A383W1B7 45-216 None
A0A1E5V4J6 281-433 None
A2Y000 109-268 None
A2X0Y7 50-231 None
A0A7R9AR00 553-707 None
A0A3B9IW87 311-461 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.