DPCstruct | MC13186

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)160 ± 15 aa
Standard deviation of domain lengths15.44
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score76.64
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)26.53
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6V8E6J6 1-176 MPHRRFDDVHEEGDVRDGERRWCEVFARVWEALVNQPLGSTFQLPVEDGHSLAFEHVGLQATVRNSLERNFLMRIAKLLGYVSDEPT…
A0A2D7VJK9 64-221 EVRMLRERLERNNLQRRVRRFTVLLPRLWGVLLRRPLGERMTFTAMTRGRPNVSFDGCDAQFETASMVERRALYAMLEASGWIRDRE…
A0A075G4S4 291-455 None
A0A2D8M6N7 531-725 None
A0A7C7TXV0 654-800 None
A0A6V8ESM6 155-311 None
A0A842PDN4 6-164 None
A0A367I3H6 71-207 None
A0A7J4M8V1 120-266 None
A0A7J4R2M5 285-437 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.