DPCstruct | MC13072

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)210 ± 34 aa
Standard deviation of domain lengths34.20
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score80.95
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)24.53
Pfam Score100.00
Assigned Pfam label(s) PF10593

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0S4LEI4 63-247 LARFCITVAHLNLAATKSGQRERNFSFLVHTSGKTSDHATDRNTIETTMNALVGMTGAAFNAFVVMLHAEAQSLYPQDDSDALIKYV…
A0A2N4SXU1 8-254 FVLSGAIKLFREAKGRKSNGWQPEPYRFRHHTMLVHESMKQADHSDLAELVRQVWQESNYQAASALQRLDALWKNDFQPVSAARAEA…
A0A1X3A6B1 49-261 None
A0A0F3QFL3 55-219 None
A0A379ZH63 6-215 None
A0A4R6PT45 470-665 None
A0A7Z0KQZ3 1-271 None
A0A7Z7GFP4 169-333 None
A0A524RVT2 168-374 None
A0A7V9J4V7 129-400 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.