DPCstruct | MC13027

Metacluster Properties and Pfam Annotations

Number of structural domains138
Mean domain length (aa)98 ± 15 aa
Standard deviation of domain lengths15.43
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score78.42
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)28.65
Pfam Score95.28
Assigned Pfam label(s) CL0005- CL0547- CL0159

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E0VFS0 8-104 TVLTVLCFTSTIVVSFSCVCSPSECEDISKDDCPGGGTVWDPCRCCRVCARIEGEACGGPHGFYGTCADGLDCIVASHASGKPVLAA…
A0A444U267 163-232 QFCHWPCKCSIKPLCAPGVSLVKDGCGCCKMCAKQVGEICNEAEVCDPHKGMYCDYSTDRPRFEVGVCAY
A0A7M5WZV1 2-106 None
A0A7N8YA34 24-115 None
A0A1D2N2M8 48-133 None
A0A7G7P0F2 11-128 None
C3ZHH1 1-134 None
A0A6P8HVB2 15-92 None
A0A5A9NDL5 15-88 None
B7PQV9 1-109 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.