DPCstruct | MC13018

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)109 ± 11 aa
Standard deviation of domain lengths10.93
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score84.25
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)29.41
Pfam Score100.00
Assigned Pfam label(s) CL0649

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J7J5B2 459-555 PETGRKHQLRVHLADGISTPILGDHKYSHRDKLAPQWLHKEILTKFNLKPMNARQMPLHLHARRLVLPNYFRNGQELTLTAKLPKFF…
A0A444V7L6 2-92 SLGLGCQILGDHKYAHNSKLAPQKLSEGFLRRLGLVQSKARHLPLHLHARQLTFPGGAGGHQEVTVSSPLPKFFLTSLKRLKIELPG…
A0A7R8X1H1 444-572 None
A0A131YZ36 150-269 None
A0A5N5SWG7 102-219 None
A0A813RXE9 203-311 None
A0A158R4L4 355-450 None
A0A0Q3PTI0 1-120 None
A0A1S3KI22 778-879 None
A0A226MLV2 535-634 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.