DPCstruct | MC13010

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)157 ± 33 aa
Standard deviation of domain lengths32.96
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score82.61
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)61.88
Pfam Score100.00
Assigned Pfam label(s) CL0196

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6P7FBS0 2-111 LESNKGRTMLEFQELMTVFQLLHWNGSLKAMRERQCSRQEVVAHYSNRALDDDMRSQMALDWIAREQESAGSIRKELNQAERELESA…
A0A444UYF1 40-186 YKEKREILSLALSQRHSEGASAQITQEFISHSVQEAASTASELMTVFQLLHWNGSLKIFRERKCSRKEVVSYYSQHRLDECFRSHMA…
A0A4W5M4J8 3-124 None
A0A6B0SHN9 67-243 None
A0A6J2DDQ9 172-281 None
A0A3Q2PAS7 10-220 None
A0A226P5W9 152-259 None
A0A3Q3X6M2 77-249 None
A0A6I8VWF9 25-162 None
A0A6P8FS98 50-233 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.