DPCstruct | MC13009

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)288 ± 22 aa
Standard deviation of domain lengths21.95
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score76.72
Mean fraction of residues predicted as intrinsically disordered0.51
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)38.22
Pfam Score65.00
Assigned Pfam label(s) CL0016- CL0672

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2J8K0H9 80-307 MKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLENNSSVLGLNGNSGAAGGGGGWNDNTSLLWAGKSLQEGATGGHSCPQAMKKWGWE…
S7MJX3 1-291 MKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLENNSSVLGLNGYSGAAGGGGGWNDNTSLLWSGKSLLEGATGGQSCPQAMKKWGWE…
A0A1L8FAF1 545-841 None
A0A811V7S8 563-857 None
T1PHZ5 275-592 None
F1QVU0 601-888 None
A0A444TTU8 202-498 None
A0A6P7S7X9 6-289 None
H3B463 149-443 None
Q7KJ08 888-1169 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.