DPCstruct | MC13002

Metacluster Properties and Pfam Annotations

Number of structural domains227
Mean domain length (aa)239 ± 43 aa
Standard deviation of domain lengths42.60
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score82.96
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)20.51
Pfam Score97.15
Assigned Pfam label(s) CL0039- CL0292- CL0344- PF14715

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A645CAL1 4-197 None
A0A1Y6M4J4 173-391 None
A0A3M1D132 110-365 None
K1Z8X5 23-229 None
A0A6L5QL77 8-273 None
M1P0Z5 1-157 None
A0A375ENK2 293-543 None
A0A0M5KV53 352-646 None
A0A662TTD1 24-257 None
A0A418WER5 121-365 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.