DPCstruct | MC12996

Metacluster Properties and Pfam Annotations

Number of structural domains22
Mean domain length (aa)174 ± 15 aa
Standard deviation of domain lengths15.33
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score79.76
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)31.39
Pfam Score100.00
Assigned Pfam label(s) PF14127

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2I0R3G2 2-155 PQDFNRQYRIALRRVRRVYPLVLEAARIIDSLDQELESIEKNRKKKKLMRKTHKALKDDFKYLLKDLYISEGKVLTKLIHRETGMTV…
A0A7X8I5D5 20-178 MPVITLPTVVVYPTRTLGNDRASREYIALAQKVRKVYPYARLAVEVLAEINDTIAKMDLERARKRYIKEYEKALLAEYKTELVKMKV…
A0A1Q3ZLM6 5-189 None
A0A2E5XC99 16-177 None
A0A136MV24 15-190 None
A0A2G2F0G9 17-188 None
A0A1M3IH65 1-179 None
A0A5Q5G1B7 1-134 None
A0A507ZH63 2-167 None
A0A401XKT6 31-211 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.