DPCstruct | MC12990

Metacluster Properties and Pfam Annotations

Number of structural domains30
Mean domain length (aa)72 ± 12 aa
Standard deviation of domain lengths12.44
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score75.75
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)52.07
Pfam Score100.00
Assigned Pfam label(s) CL0104

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2I0AE82 104-163 MAAVEKQLEEMGVRFVRRTVEEGGIFVDQIFFHDPDGFMIEICNCENFPVIPLLPAVNES
A0A4V4H677 1-70 MGAMEQRLKDLGVKYLRRTINEEEGSPIDQLFFNDPDGFMIEICNCESLELVPAGSLGRLRLPWRSPRPP
A0A811R131 42-109 None
A0A6I9RIC9 140-237 None
A0A835APS0 222-294 None
A0A0L9V3V5 1-74 None
A0A6J5VL31 121-177 None
A0A4S8IKX1 14-97 None
A0A3L6R3N4 2-84 None
A0A1D6MK37 2-86 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.