DPCstruct | MC12989

Metacluster Properties and Pfam Annotations

Number of structural domains7
Mean domain length (aa)181 ± 7 aa
Standard deviation of domain lengths7.41
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score81.78
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)56.07
Pfam Score100.00
Assigned Pfam label(s) PF05817

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S4ETR5 87-278 SESHRFAALELFTPLHGSFGSLEEASEALRTFEILGIGKELNIRDSTCPSVVDTLGSSSSSLKDLFYALRVNKLLKCETNEEVFAGI…
A0A835VKI3 3-178 RRGILLLLCLLCATIVSCRASSVLRPVSEAHRSTALELFVPFDGSYGSLEDSYEALKTYQILGLDKIFDASLATCKSVIENLDSPSA…
A0A2J6JQ23 28-219 None
A0A2R6QSE8 14-185 None
A0A6A2YF73 1-181 None
A0A6A6KD05 2-181 None
A0A1S4CHX5 26-200 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.