DPCstruct | MC12983

Metacluster Properties and Pfam Annotations

Number of structural domains22
Mean domain length (aa)75 ± 5 aa
Standard deviation of domain lengths4.63
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score89.29
Mean fraction of residues predicted as intrinsically disordered0.14
Mean length-normalized TM-Score0.90
Mean intra-cluster local Distance Difference Test score0.89
Mean intra-cluster sequence similarity (%)67.77
Pfam Score100.00
Assigned Pfam label(s) CL0110

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q0E3N4 13-96 FYVKVDDDVHVNIATLGQILSNHALKPRVYIGCMKSGPVLTEKGVRYYEPEHWKFGEPGNKYFRHATGQLYAISKDLATYISIN
A0A4S8K230 1-71 MLIANLARHRTTPRVYIGCMKSDQVLFQRDAKYHEPEFWKFGEEGNKYFRHATGQIYAISKDLALYISINA
A0A1R3HRB1 236-311 None
A0A811NW58 931-1002 None
A0A5C7IPV2 63-134 None
A0A453S720 165-241 None
A0A6A6LQL9 94-166 None
A0A816R2S8 474-544 None
A0A452XFZ1 57-141 None
A0A2G2X598 102-175 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.