DPCstruct | MC12980

Metacluster Properties and Pfam Annotations

Number of structural domains38
Mean domain length (aa)59 ± 5 aa
Standard deviation of domain lengths5.06
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score74.23
Mean fraction of residues predicted as intrinsically disordered0.48
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.91
Mean intra-cluster sequence similarity (%)68.32
Pfam Score98.15
Assigned Pfam label(s) CL0267- PF00410

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2A4AVS8 1-41 MGPQHLVGETVFGVAHIFASFNDTFVHVTDLSGRETIARVT
A0A4S8JWY8 38-92 RRKTREPKEYNVLLGPAVREGEQVFGVAHIFASFNDTCIHVTDLSGRETLVRITG
A0A0D2ZT05 52-113 None
A0A426XX98 186-245 None
A0A4U0W250 1-58 None
A0A1U8PPB3 80-139 None
A0A4S8IE71 74-133 None
A0A226NSV9 2-69 None
A0A816PCU3 336-392 None
A0A6A3CLD1 416-474 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.