DPCstruct | MC12978

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)127 ± 8 aa
Standard deviation of domain lengths7.99
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score77.42
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)51.40
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A4Q4W9 1-123 MVKLASARDFRTYGTGLTRNRCEYINAGLYLFATIVFCCAFASQFSSEPRSGLVLFLISFAIILIVNVHDLFAHLSGIDFRLPLMAF…
A0A4S8JV87 1-134 MVKLASARESRTYGPGSRLARTRWEYINAGLYLFATALLVGGFAAQISSVSSAGAKSGLVAVLVALALLLAVNAHDLVAHLAAVDYC…
A0A453A286 1-128 None
A0A453A231 84-206 None
A0A2K1KWW1 1-124 None
B6SJE1 1-144 None
A0A6G1EQ60 1-117 None
A0A444CGG5 1-122 None
A0A6N2KJB3 115-239 None
A0A445L4G6 1-122 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.