DPCstruct | MC12974

Metacluster Properties and Pfam Annotations

Number of structural domains308
Mean domain length (aa)135 ± 39 aa
Standard deviation of domain lengths38.53
Length coefficient of variation0.28
Mean AlphaFold2 pLDDT confidence score85.53
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)15.38
Pfam Score52.71
Assigned Pfam label(s) PF07930- CL0013- PF11954- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H2XW79 14-106 None
A0A7W1W2X1 295-393 None
A0A7W1TTP6 29-124 None
A0A6J4E238 111-288 None
A0A7Y5NT33 329-514 None
A0A2V9MPP8 1-74 None
A0A357Z8Y4 12-109 None
A0A812JPU7 520-619 None
A0A7W1KQK9 1-100 None
A0A1F2S5M9 168-280 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.