DPCstruct | MC12974

Metacluster Properties and Pfam Annotations

Number of structural domains308
Mean domain length (aa)135 ± 39 aa
Standard deviation of domain lengths38.53
Length coefficient of variation0.28
Mean AlphaFold2 pLDDT confidence score85.53
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)15.38
Pfam Score52.71
Assigned Pfam label(s) PF07930- CL0013- PF11954- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Y9W398 29-135 AERLANLHFGRHEPRASVPIDPPLLETYTGCYRLGPKYFVRVTTEAGALNIHARGQEPLRLAYAGADSFFCQVRDMQIDFQRADEGS…
A0A838KS61 2-75 AGDWYWGNVAMTAAATTDGFTLTTEGAARAFVEVGTDTYRGGNGYFAGEELRVVRRPDSSVSHLEVVTFIFTRT
B9XG07 399-504 None
G3JFC5 884-1104 None
H8GUR1 192-340 None
A0A6L7JTP1 130-227 None
A0A7V2ZHR9 1-86 None
A0A523E6Y8 108-240 None
A0A2E0UT53 285-405 None
A0A2V7W6I0 91-211 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.