DPCstruct | MC12965

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)181 ± 25 aa
Standard deviation of domain lengths24.52
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score91.21
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)42.88
Pfam Score100.00
Assigned Pfam label(s) CL0088

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S9A380 24-180 LLDEKHHHFMANTLILVTFDENHTYTSSNRVLGMLLGDAVPKKLIGTTDPQYYNHYSEISTVEANWNLHTLGRWDVGANIFSVVADQ…
A0A0D1WSI0 401-591 SDGHDTSVTVAGAWTRNFLEPLLKDSRFMKNTMVLVHFDENHTYTIQNRVLGILLGDAVPTSLAGTTDSNFYDHYSEISTVEANWDL…
A0A2S4PV59 114-256 None
A0A261XSS2 1-147 None
A0A0E9NIR5 321-503 None
A0A1C7MH11 707-948 None
A0A0V1PWM7 1-152 None
A0A094IVY1 214-394 None
A0A0L1JG17 213-394 None
A0A5C3ENC2 1-181 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.