DPCstruct | MC12952

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)108 ± 9 aa
Standard deviation of domain lengths9.10
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score93.55
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)33.15
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3S4UA40 17-129 SSAVENPPVLQDNIVLKEALHRVLRLPVVAEKTFLITIGDRSVTGMVARDQMVGPWQIPVSDVAITTASLDSYHGEAMAMGERAPVA…
A0A446JA11 67-175 APEITLMDVLKRVLKLPSVCSKRFLTTKVDRCVTGLVAQQQTVGPLQLPLADVAVVAQTYTDLTGGACAIGEQPIKGLLNPEAMARL…
A0A7E4RDR1 457-561 None
A0A329P9D6 190-303 None
A0A7X9KTU5 619-723 None
A0A1V3WVS2 147-265 None
V9GLD2 146-263 None
A0A0V0RYY1 12-99 None
A0A3B8ZXB9 565-674 None
A0A812M9D7 81-177 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.