DPCstruct | MC12947

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)128 ± 15 aa
Standard deviation of domain lengths14.71
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score90.87
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.90
Mean intra-cluster sequence similarity (%)77.00
Pfam Score100.00
Assigned Pfam label(s) PF00421

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K0RJ67 283-409 MRSPSGEIIFGGETMRFWDLRAPWVEPLRGPNGLDINKIKNDIQPWQERRAAEYMTHAPLGSLNSVGGVATEINSVNYVSPRSWLCC…
A0A151R6I0 1-127 MRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLAT…
V4KQV8 148-265 None
A0A7S0CKW5 239-382 None
A0A823A6C2 410-534 None
A0A2N9H999 539-670 None
A0A7J6ENX8 1-127 None
A0A396I1Y2 167-273 None
A0A650G361 330-478 None
A0A445BWI7 1-107 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.