DPCstruct | MC12940

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)142 ± 13 aa
Standard deviation of domain lengths12.62
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score71.63
Mean fraction of residues predicted as intrinsically disordered0.48
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)34.50
Pfam Score100.00
Assigned Pfam label(s) CL0184

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0H1BG28 1-168 MYEVLGQLGLYGMFIIGVQAAIFDRESFASATWNGQVGGYLTGYTFCLFIFYSLAPILFRLASAAFFNISLLTANFWGVIIGVNVFK…
A0A1D1Y4F2 1-122 MLGVFGMLVSICEIVLLERKTLESVKWSPTVISLFAGFAVAAFLFYTVVPFILKMSGATLFNLSLLTSDMWAVVIRIFFYRQQVDWL…
A0A8B6ERD0 126-254 None
E4XVX6 95-244 None
A0A5A9MXE6 88-231 None
A0A337SDZ5 167-298 None
A0A446J4F5 1-152 None
A0A0C9YA61 49-182 None
A0A401PBU5 66-204 None
A0A4S4LFB9 170-314 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.